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Clomid is not an anabolic/androgenic steroid. Since it is
a synthetic estrogen it belongs, however, to the group of
sex hormones. In school medicine Clomid is normally used to
trigger ovulation. Clomid, by setting in motion the process
of releasing hormones, stimulates the release of
gonadotropin and triggers ovulation in women with
anovulatory cycles and who are sterile because of this.
Although this is actually a drug destined for women its
effect on men is undisputed. The manufacturer of Dyneric,the
Merrell Dow Pharma GmbH, writes in its package insert for
the German version of Clomid: "Dyneric causes an
improved activity between mid-brain, pituitary gland, and
ovaries." What however is not mentioned is that Dyneric
also improves the activity between mid-brain (hypothalamus),
pituitary gland thypophysis), and testes in men. Clomid has
a strong influence on the hypothalamohypophysial testicular
axis. It stimulates the hypophysis to release more
gonadotropin so that a faster and higher release of FSH
(follicle stimulating hormone) aud LH (luteinizing hormone)
occurs. This results in an elevated endogenous (body's own
testosterone level. Clomid is especially effective when the
body's own testosterone production, due to the intake of
anabolic/androgenic steroids, is suppressed. In most cases
Clomid can normalize the testosterone level and the
spermatogenesis (sperm development)within 10-14 days. For
this reason Clomid is primarily taken after steroids are
discontinued. At this time it is extremely important to
bring the testosterone production to a normal level as
quickly as possible so that the loss of strength and muscle
mass is minimized. Even better results can be achieved if
Clomid is combined with HCG or when Clomid is used after the
intake of HCG. The difference between Clomid and HCG lies in
the fact that Clomid has a direct influence on the
hypothalamus and the hypophysis, thus regenerating the
entire regulating cycle while HCG imitates the effect of the
luteinizing hormone (LH) which stimulates the Ledig's cells
fo produce more testosterone. Since HCG, unlike Clomid,
leads to a distinctly elevated plasmatestosterone level
within a few hours, many athlets first take HCG and then
Clomid (see also HCG).
Paradoxically, although
Clomid is a synthetic estrogen it
also works as an antiestrogen. The reason is that
Clomid has
only a very low estrogenic effect and thus the stronger
estrogens which, for example form during the aromatization
of steroids, are blocked at the receptors. These would
include those that develop during the aromatizing of
steroids. This does not prevent the steroids from
aromatizing but the increased estrogen is mostly deactivated
since it cannot attach to the receptors. The inereased water
retention and the possible signs of feminization can thus be
reduced or even completely avoided. Since the antiestrogenic
effect of Clomid is lower than those found in Proviron,
Nolvadex, and Teslac it is mainly taken as a testosterone
stimulant. From the German book Doping By Brigitte Berendonk
the reader can learn that Clomid is not only used in
bodybuilding: "During the 1980's Clomiphene (table 2)
has been used, a medication that promotes the production of
the body's own stimulating hormone, gonadotropin, which in
turn increases the testosterone level. - It is, for example,
administered to women as a so-called antiestrogen to trigger
ovulation ("ovulation stimulator").Clomiphene
(usually the Hungarian compound Clostilbegyt) was used by
rowers (resp. Prof. Dr. Herbert Gurtler) and weightlifers
(Dr Lathan; p. 187) since the late 1970's. Increasingly, it
was used in other sports disciplines as well, including
track and field athletics. Riedel, at the time, happily made
the handwritten entry in his notebook: "Substance that
is not an anabolic: generally traceable but is not a doping
substance." The dosages were horrendous. I found
entries of up to l5 times 100mg daily and the report that
the positive effect lasts up to 20 days after the last
tablet is taken. And it was already assured since 1982 that
the increased testosterone production after doping with
Clomiphene did not reveal traits of the T/E quotient
(testosterone/epitestosterone quotient, the author)during
doping tests.
Side effects of Clomid are very rare if reasonable dosages
are taken. Possible side effects are climacteric hot flashes
and occasional visual disturbances which can manifest
themselves in blurred vision, giving flickering or flashing.
Should visual distuibances occur, the manufacturer
recommends discontinuing Clomid treatment. Inadequate liver
functions cannot be excluded;however,they are very unlikely
in women enlargement of the ovaries and abdominal pain can
occur since Clomid stimulates the ovaries. When taking
Clomid multiple pregnancies are possible as well. As for the
dosage, 50-100 mg/per day(1-2 tablets) seems to be
sufficient. The tablets are usually taken with fluids after
meals. If several tablets are taken it is recomended that
they be administered in equal doses distributed throughout
the day. The duration of intake should not exceed 10 to 14
days. Most athlets begin with 100 mg/day taking one 50mg
tablet every morning and evening after meals. After the
fifth day the dosage is often reduced to only one 50mg
tablet per day. It is normally not necessary to take the
compound for more than 10 days in order to increase the
endogenus testosterone production. Since Clomid should not
be taken for a prolonged time its application as an
antiestrogen must be excluded because, for that purpose, it
would have to be taken for several weeks. Clomid is
relatively expensive. A package with 10 tablets costs
approx. $35 - 45 on the black market. Fortunately, since the
intake is only for a brief time, the financial burden
usually becomes acceptable. The foreign compounds such as
the Spanish Omifin are considerably cheaper and cost less
than $2 per tablet
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